Search results for "Tecnología médica"
showing 10 items of 27 documents
Clinical effect of diode laser on peri-implant tissues during non-surgical peri-implant mucositis therapy: Randomized controlled clinical study
2019
Background: The aim of this study is to evaluate the response to the non-surgical treatment of peri-implant mucositis using the diode laser as an adjuvant therapy in patients with implant-supported restorations, in terms of clinical variables, with respect to those patients in whom conventional non-surgical therapy is used. Material and Methods: Randomized controlled clinical trial with simple blind 3 months follow-up. Two groups of patients were established, the non-surgical mechanical debridement of the affected implants was performed in the control group (n = 34) and the diode laser therapy was also performed in the test group (n = 34). The implant was considered the study subject; the v…
A new mass spectrometry-based method for the quantification of histones in plasma from septic shock patients.
2017
The aim of this study was to develop a novel method to detect circulating histones H3 and H2B in plasma based on multiple reaction monitoring targeted mass spectrometry and a multiple reaction monitoring approach (MRM-MS) for its clinical application in critical bacteriaemic septic shock patients. Plasma samples from 17 septic shock patients with confirmed bacteraemia and 10 healthy controls were analysed by an MRM-MS method, which specifically detects presence of histones H3 and H2B. By an internal standard, it was possible to quantify the concentration of circulating histones in plasma, which were significantly higher in patients, and thus confirmed their potential as biomarkers for diagn…
Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations
2016
This work was supported by Spanish Ministry of Economy and Competitiveness (MINECO) Grants SAF2010-16044 and SAF2013-46663-R (to V.A.), SAF2011-30312 and SAF2014-58286-C2-1-R (to L.H.-M.), SAF2011-30088 (to E.D.), and SAF2014-52413-R (to C.L.-O.) and Fondo de Investigación Sanitaria del Instituto de Salud Carlos III Grants RD12/0042/0028 (to V.A.), RD12/0042/0011 (to J.T.), and RD12/0042/0002 (to L.H.-M.), with cofunding from the Fondo Europeo de Desarrollo Regional and the Progeria Research Foundation. J.A.G. is the recipient of a U-Mobility Grant from the Marie Curie cofunding of Regional, National and International Programme (Grant 246550). The Instituto Universitario de Oncología is sup…
MTA apical barrier: In vitro study of the use of ultrasonic vibration
2016
Background: The apexification is the first alternative treatment on a permanent tooth when, after a tooth trauma and in the presence of immature apex trauma, pulp necrosis occurs. Many studies have demonstrated the efficacy of mineral trioxide aggregate (MTA) as apical sealing material of choice in these cases, but has a degree of filtration as all other materials. The objective of this study was to analyze the seal ability of MTA on the duct walls in immature teeth unirradicular apexes, using indirect vibration. Material and Methods: The study was conducted on 45 teeth divided into 3 groups: Group A or control group in which no vibration for placing the MTA was used, Group B and C or group…
Relationship between internal root resorption and dens in dente
2020
Background The aim is to report the treatment and follow-up of three lateral incisors with internal root resorption and dens in dente as a possible cause for their development, managed by root canal treatment and apical obturation with MTA or gutta-percha. Case description This case report presents three clinical cases in which dens invaginatus type 2 is shown as a potential cause for the development of internal root resorption. Two cases were filled with a MTA apical plug technique and one with gutta-percha, and all were follow-up through time. Practical implications The incidence of the association of internal root resorption with dens invaginatus may be underestimated and should be studi…
Análisis biomecánico de las actividades de subir y bajar escaleras en personas con patologías de rodilla
2016
La patología de la rodilla produce discapacidad para las actividades de la vida diaria, lo cual supone un reto médico, social y económico creciente. Es necesario contar con mejores herramientas de valoración con la finalidad de evaluar los nuevos tratamientos y protocolos, orientar mejor los programas para cada paciente y hacerlos más eficaces y eficientes. Las técnicas biomecánicas se utilizan para la valoración funcional de las personas con patologías de rodilla. El objetivo del trabajo es mejorar el conocimiento sobre las repercusiones funcionales que produce la patología de rodilla en las actividades de subir y bajar escaleras. Para ello se ha desarrollado un protocolo de valoración que…
Síntesis y caracterización de scaffolds poliméricos para la ingeniería de tejidos
2013
El desarrollo del campo de la ingeniería de tejidos surge ante la necesidad de dar solución a las deficiencias asociadas a la sustitución de tejidos cuando se han producido pérdidas irreparables de los mismos o no funcionan correctamente. Muchos tipos de células necesitan scaffolds para guiar el desarrollo de nuevos tejidos con la función apropiada, servir como sustrato para la adhesión celular y al mismo tiempo proporcionar un soporte mecánico para el nuevo tejido que ha crecido. El objetivo principal de este trabajo ha sido desarrollar métodos de síntesis de scaffolds poliméricos, basados en el método convencional denominado colado de sólidos en combinación con el lixiviado de partículas,…
Morphometric and histopathological analysis of articular cartilage regeneration on tissue engineered scaffolds
2014
El objetivo de este trabajo es estudiar la regeneración in vivo de cartílago articular inducido por scaffolds manufacturados mediante técnicas de ingeniería tisular, evaluando la formación de neotejido inducido por diferentes andamiajes, mediante técnicas histológicas y morfométricas. Previo al presente trabajo, en el centro de biomateriales se han diseñado y fabricado scaffolds bioestables compuestos por copolímeros de poli-etilacrilato e hidroxietil-acrilato p(EA-co-HEA), con 90% unidades monoméricas de etilacrilato, en los que se ha variado la cantidad de entrecruzador, obteniendo así 4 grupos con distintas durezas. Estos biomateriales, en forma de discos, se han implantado tras perforar…
The importance of the posterior joint space for functional mandibular movements: A laboratory cross-sectional study
2018
Background: The search for the ideal, healthy and reproducible position of the condyles is of utmost importance for dental diagnosis and treatment. Thus, the objective of this laboratory cross-sectional study was to verify the relationship between the posterior joint space and the mandibular lateral movements. Material and Methods: Dental casts from 15 women and 15 men with normal mastication, 28 natural teeth and no history of temporomandibular disorders or pain, were fabricated and mounted on a fully adjustable articulator. From the maximum intercuspal position, condylar displacement was evaluated and measured on the working and nonworking sides during mandibular lateral movement, both to…
Behavior of polyether-ether-ketone (PEEK) in prostheses on dental implants. A review.
2020
Background The development of new and innovative materials such as high performance polymers (PEEK) opens a wide therapeutic range in implant prostheses. They are presented as alternative materials to metal and zirconium alloys in the manufacture of structures and attachments for implant prostheses and fixed and removable dental substitutes. The objective of this review is to know the characteristics of this material and thus assess its advantages and disadvantages in its possible applications in prostheses on dental implants. Material and methods A bibliographic search was carried out through the PubMed and Scopus search engines, of articles published from 2007 to 2020, excluding all artic…